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Naringenin

 
Product Name Naringenin
Latin Name Naringenin
Molecular Formula C15H12O5
Molecular Weight 272.25
CAS NO 93602-28-9
Appearance White-like powder
Product Content ≥98%  
Analytical Method HPLC
   
Product Origin

Citrus paradisi Macfadyen

   
Action and Uses Naringenin is a potent inhibitor of the cytochrome p450 liver enzymes: CYP1A2, CYP3A3 and CYP3A4. There is however, considerable inter-individual variability in the effects of grapefruit juice on drug metabolism, in part due to 1) amount of naringenin formed by an individual, 2) amount of naringin present in a brand of grapefruit juice, 3) dilution of grapefruit juice used, and 4) other substances in grapefruit juice accounting for the interaction.2 Researchers at the University of Western Ontario in London discovered, while using various juices to hide the taste of a test substance given to patients along with their drugs as part of a cancer trial, that there was a synergistic or more effective action of the drug to breast cancer when it was given with Grapefruit Juice. From here, researchers launched studies of other fruits to find out why, and this is what they discovered. Human breast cancer cells in test tubes that were estrogen-insensitive; that is, the cells did not need estrogen to cock and prime them into maligency, respond well to a flavonoid found in grape juice, naringenin. Naringenin proved almost 8 times more potent at halting breast cancer cells's growth than another flavonoid, genestein from soy beans. You can now get the extract of the grape in capsule form. Ask for Resveratrol at your favorite health food store.
Analysis
  Product content Naringenin≥98%
Sieve analysis 100% pass 80 mesh
Loss on Drying ≤1.0%
Residue on Ignition ≤1.0%
Heavy Metal <20ppm
As <2ppm
Residual Solvents Eur.Pharm.2000
Microbiology  
Total Plate Count <1000cfu/g
Yeast & Mold <100cfu/g
E.Coli Negative
Salmonella Negative
     
Conclusion Conform with specification
   
Storage Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation
   
Shelf life 2 year when properly stored
 
 
 
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